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Hypertension LOPRESOR metoprolol tartrate ; is usually used in conjunction with other antihypertensive agents, particularly a thiazide diuretic, but may be used alone see Indications ; . The dose must always be adjusted to the individual requirements of the patient, in accordance with the following guidelines. LOPRESOR treatment should be initiated with doses of 50 mg b.i.d. If an adequate response is not seen after one week, dosage should be increased to 100 mg b.i.d. In some cases the daily dosage may need to be increased by further 100 mg increments at intervals of not less than two weeks up to a maximum of 200 mg b.i.d., which should not be exceeded. The usual maintenance dose is within the range of 100-200 mg daily.
LANCETS, ULTRAFINE II see LANCETS LANOLIN Brand Name s ; : Lanolin Ointment LANOXIN see DIGOXIN LANOXIN PEDIATRIC see DIGOXIN LANTUS see INSULIN, GLARGINE LASIX see FUROSEMIDE LATANOPROST Brand Name s ; : Xalatan Solution, ophthalmic: 0.005% LAXATIVE see BISACODYL LEUCOVORIN Brand Name s ; : Leucovorin Tablets: 5mg LEUPROLIDE Brand Name s ; : Lupron Depot Kit: 3.75mg 1Month ; Kit: 11.25mg 3Month ; LEVALBUTEROL Brand name s ; : Xopenex HPA Inhaler: 15gm ea LEVAQUIN see LEVOFLOXACIN LEVEMIR see INSULIN, DETEMIR LEVOCABASTINE Brand Name s ; : Livostin Solution, ophthalmic: 0.05% LEVOFLOXACIN Brand Name s ; : Levaquin Tablets: 250mg 500mg 750mg LEVONORGESTREL Brand Name s ; : Plan B Tablets: 0.75mg LEVOTHYROXINE Brand Name s ; : Synthroid Tablets: * ALL STRENGTHS * LIBRAX see CHLORDIAZEPOXIDE CLIDINIUM LIBRIUM see CHLORDIAZEPOXIDE LIDEXE see FLUOCINONIDE LIDOCAINE Brand Name s ; : Viscous Lidocaine, Xylocaine Gel jelly: 2% Ointment: 5% Solution: 2% Solution, topical: 4% LIGHT MINERAL OIL see MINERAL OIL LINDANE Brand Name s ; : Lindane Shampoo: 1% LIORESAL see BACLOFEN LIOTHYRONINE Brand Name s ; : Cytomel Tablets: 25mcg LIQUITEARS see ALCOHOL, POLYVINYL LISINOPRIL Brand Name s ; : Zestril, Prinivil Tablets: 5mg 10mg 20mg LITHIUM see LITHIUM CARBONATE LITHIUM CARBONATE Brand Name s ; : EskalithCR, Lithium Capsules: 300mg Tablets, extended release: 450mg LIVOSTIN see LEVOCABASTINE LO OVRAL28 see ETHINYL ESTRADIOL NORGESTREL LODINE see ETODOLAC LOESTRIN see ETHINYL ESTRADIOL NORETHINDRONE LOMOTIL see ATROPINE DIPHENOXYLATE LONITEN see MINOXIDIL LOPERAMIDE Brand Name s ; : Imodium Capsules: 2mg LOPID see GEMFIBROZIL LOPRESSOR see METOPROLOL LORATADINE Brand Name s ; : Claritin Syrup: 5mg 5ml Tablets: 10mg LORAZEPAM Brand Name s ; : Ativan Tablets: 0.5mg 1mg LOSARTAN Brand Name s ; : Cozaar Tablets: 25mg 50mg 100mg LOTREL see AMLODIPINE BENAZEPRIL LOVENOX see ENOXAPARIN LUBRICANT Brand Name s ; : KY Jelly, Surgilube LUPRON DEPOT see LEUPROLIDE MEDROXYPROGESTERONE ACETATE Brand Name s ; : Depoprovera, Depo provera Contraceptive, Provera Injection: 150mg ml 400mg ml Tablets: 2.5mg 10mg MEFENAMIC ACID Brand Name s ; : Ponstel Kapseals Capsules: 250mg MEGACE see MEGESTROL MEGESTROL Brand Name s ; : Megace Tablets: 40mg MELLARIL see THIORIDAZINE MELOXICAM Brand Name s ; : Mobic Tablets: 7.5mg 15mg MEPERIDINE Brand Name s ; : Demerol Tablets: 50mg MEPHYTON see PHYTONADIONE MERCAPTOPURINE Brand Name s ; : Purinethol Tablets: 50mg MESALAMINE Brand Name s ; : Asacol, Pentasa, Rowasa Capsules, extended release: 250mg Tablets, enteric coated: 400mg Enema: 4gm 60ml Suppositories: 500mg METADATE CD see METHYLPHENIDATE METAMUCIL TYPE see PSYLLIUM METAPROTERENOL Brand Name s ; : Alupent Oral inhaler: 650mcg dose, 200 doses Solution, nebulizer: 5% Solution, nebulizer premixed ; : 0.6% Syrup: 10mg 5ml Tablets: 10mg METFORMIN Brand Name s ; : Glucophage Tablets: 500mg 850mg 1000mg METHERGINE see METHYLERGONOVINE MALEATE METHIMAZOLE Brand Name s ; : Tapazole Tablets: 5mg METHOCARBAMOL Brand Name s ; : Methocarbamol Tablets: 500mg METHOTREXATE Brand Name s ; : Methotrexate Tablets: 2.5mg METHYLDOPA Brand Name s ; : Aldomet Tablets: 250mg 500mg METHYLERGONOVINE Brand Name s ; : Methergine Tablets: 0.2mg.
Received in original form March 16, 2006; accepted in final form March 16, 2006 ; Supported by the National Institutes of Health. Grants R01 HL65611 and R01 HL082504 both were awarded to J.A.V. Correspondence and requests for reprints should be addressed to Judith A. Voynow, M.D., Duke University Medical Center, Erwin Road, 302 E Bell Building, Durham, NC 27710. E-mail: voyno001 mc.duke Proc Thorac Soc Vol 3, 2006 DOI: 10.1513 pats.200603-045MS Internet address: atsjournals. We comply with the honcode standard for health trust worthy information: verify here and trazodone. Haronian has also been a member of the clinical faculty of the yale school of medicine since 1994 and has served as the director of the cardiac catheterization program at yale-new haven hospital since 200 paul koehler, director. Resitant closure ; cap and stored at controlled room temperature 20 C 25oC ; for 6 months. Stability samples were collected at 0, 1, 3, and 6 months, and dissolution tests were performed to study the effect of long-term storage on these formulations. Bioavailability Studies An open, randomized, fasting, single-dose, 3-propranolol treatment, crossover study was performed with 14 healthy, nonsmoking, male and female subjects. The treatments were as follows: 1 ; small batch, 2 ; large batch, and 3 ; Inderal 80-mg tablet. After an overnight fast, subjects were administered 1 tablet, and blood samples were collected over a 24-hour period. Plasma samples were stored at - 80oC before analysis with a validated HPLC method. An open, randomized, fasting, single-dose, 2-metoprolol treatment crossover study was performed with 14 healthy, nonsmoking subjects. After an overnight fast, subjects were administered 1 tablet small or large batch ; , and blood samples were collected over an 18-hour period. Samples were separated and the plasma samples were analyzed for metoprolol concentrations. The protocols for propranolol and metoprolol were approved by the Institutional Review Board at the clinical site Harris Laboratories, Lincoln, NE ; , the University of Maryland Institutional Review Board, and the Research Involving Human Subjects Committee at the FDA. All subjects gave written informed consent. Analytical Methods. Propranolol was analyzed by a validated HPLC method using fluorescence detection and solid-phase extraction. The analytical column used was a Zorbax C-8 reversephase column Mac-Mod Analytical, Inc., Chadds Ford, PA ; , and the mobile phase consisted of 0.25% phosphoric acid and acetonitrile 74: 26, vol vol ; . The validated range of quantifiable concentrations for the analyte was between 3 and 200 ng mL. The intraday and interday coefficients of variation were no more than 12% for all standard and control samples. A gas chromatography method for quantitation of metoprolol in human plasma was developed and validated by Harris Laboratories. The method involved extraction of the drug and internal standard from the sample and triamterene. Non-vertebral fracture None of the studies reviewed in this section demonstrated that exercise had a statistically significant protective effect in relation to nonvertebral fracture Table 59 ; . Again, it was not appropriate to pool the results. NOTES TABLE 1. Results of serological tests for B. henselae- and T. gondii-specific antibodies and trimox. Allende sought reforms in the national health service and other institutions that would have achieved structural changes throughout society. Because of his advocacy of a unified health service in the public sector, the Chilean national medical association Colegio Mdico ; feared the effects of Allende's policies on private practice and therefore frequently opposed him, especially before the coup of 1973. American Journal of Pharmaceutical Education Vol. 66, Summer 2002 and triphasil.

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This is characterised by unpredictable attacks of anxiety with pronounced physical autonomic symptoms not related to any particular situation. Commonly described fears are that of `going mad', dying etc.

In a method aspect of the present invention, of atenolol, pindolol, esmolol, propranolol, or metoprolol is administered to a patient through an inhalation route and ultram.

[1] Remme WJ, Swedberg K, Task force for the Diagnosis and Treatment of Chronic Heart Failure, European Society of Cardiology. Guidelines for the diagnosis and treatment of chronic heart failure. Eur Heart J 2001; 22: 152760. [2] Metra M, Nardi M, Giubbini R, dei Cas L. Effects of short- and long-term carvedilol administration on rest and exercise hemodynamic variables, exercise capacity and clinical conditions in patients with idiopathic dilated cardiomyopathy. J Coll Cardiol 1994; 24: 167887. [3] Krum H, Sackner-Bernstein JD, Goldsmith RL et al. Double-blind, placebo-controlled study of the longterm efficacy of carvedilol in patients with severe chronic heart failure. Circulation 1995; 92: 14991506. [4] Kukin ML, Kalman J, Charney RH et al. Prospective, randomized comparison of effect of long-term treatment with metoprolol or carvedilol on symptoms, exercise, ejection fraction, and oxidative stress in heart failure. Circulation 1999; 99: 264551. [5] Sanderson JE, Chan SKW, Yip G et al. Beta-blockade in heart failure. A comparison of carvedilol with metoprolol. J Coll Cardiol 1999; 34: 15228. [6] Metra M, Giubbini R, Nodari S, Boldi E, Modena MG, dei Cas L. Differential effects of beta-blockers in patients with heart failure. Circulation 2000; 102: 54651. [7] Genth-Zotz S, Zotz RJ, Sigmund M et al. Metoprolol in patients with mild to moderate heart failure: effects on ventricular function and cardiopulmonary exercise testing . Eur J Heart Fail 2000; 2: 17581. [44]. Data on older patients are scarce: one retrospective study of those aged 6089 with myocardial infarction treated with metoprolol found reversible adverse reactions in 10.5% of patients [45]. More data are available in elderly patients without myocardial infarction: in the STOP-Hypertension study, treatment withdrawal was no more common in the treatment than the placebo group [39]. In one study, side effects as assessed by a self administered questionnaire ; were no more common in the treatment than the control group [40]. In general, cardioselective b-blockers have not been associated with important differences in well-being when compared with angiotensin-converting enzyme inhibitors and calcium antagonists in hypertensive patients at a range of ages [44]. Very few studies have compared the frequency of adverse reactions and tolerability in younger and older patients. Intuitively, a greater incidence of adverse reactions might be expected in older patients. However, overall tolerability in this age group appears to be reasonably good [39, 40, 45, 46] and valtrex. 3.6. School Health: Regular check ups, appropriate treatment including deworming, referral and follow-ups, for example, toprol 50 mg. 1872 Nikolaidis et al. Carvedilol Versus Metoprolol Succinate in DCM JACC Vol. 47, No. 9, 2006 May 2, 2006: 187181 and vasotec. This drug is used for angina pectoris chest pain due to not enough oxygen to your heart ; , hypertension, heart rhythm irregularities, to prevent a second heart attack, prevention for migraine headaches, to stop tremors, to reduce pain, narcotic withdraw, glaucoma, phobias, and to decrease side effects to anti-psychotic medication.

Burrill & Company assists life science companies to identify, negotiate and close strategic partnerships and merger and acquisition transactions providing access to resources, technologies or collaborations essential for executing company business plans. Service lines include: Strategic Partnering--From early-stage research, to product development and commercialization Merger & Acquisitions--Transactions across life sciences Spin-Outs and Divestitures--To create a new company or build value in an established entity Financing--Advisory and private placement Advisory Services--Defining the role of transactions in achieving strategic objectives and verapamil. Online canadian pharmacy - online drugstore cheap prescription drugs - cheapest drug pharmacy - cheap meds online - buy cheap drugs - cheap drugs online - discounted prescription drugs - cheap medications - inexpensive prescription - canada pharmacy - canadian prescription drugs - online canada pharmacy - top 100 prescribed drugs - top 100 ordered medications - top 100 medications - order drugs - discounted drugs - lasikmap a-b acetaminophene - codeine albuterol alendronate allopurinol alprazolam amantadin ambein amitriptyline amlodipine amoxicillin amoxil atacand azithromycin bupropion caltrate carisoprodol celecoxib cetirizine ciprofloxacin citalopram clonazepam clopidogrel codeine contraceptive patch cyclobenzaprine diamicron diazepam diltiazem dyazide effexor enalapril escitalopram esomeprazole ezetimibe fenofibrate fexofenadine fluoxetine fluticasone fluticasone - salmeterol folic acid furosemide gabapentin glipizide glyburide hydrochlorothiazide ibuprofen irbesartan isoptin isosorbide keflex lansoprazole levofloxacin levothyroxine lipitor lorazepam losartan lotrel metformin methylprednisolone metoprolol montelukast naproxen nitrofurantoin norvasc omeprazole oral contraceptive oxycodone thursday, december 29, 2005 - atacand - atacand attention: do not take candesartan if you are pregnant or breast-feeding. Prerequisite pharmacokinetic analyses e.g., blood and tissue concentration distribution, CNS uptake, and biological half-life ; at appropriate time intervals, from mice that have received candidate compounds, including radiolabeled compounds. Gross histopathologic analysis of tissues harvested from neonatal lethal and adult lethal mouse models of CNS disease, including muscle and CNS tissue. Collection, preparation, shipping, and storage of blood and neuronal tissue specimens for analysis of RNA and protein levels at other facilities. Accurate, efficient, and frequent exchange of data with other institutions, preferably electronically. Efficient and frequent exchange of materials, including compounds, biological samples, and special supplies, with other institutions and vicoprofen and toprol, for example, toprol depression. Bellaspas Tabs Benicar olmesartan ; US only Bentylol Dicyclomine Hydrochloride ; Bentylol Dicyclomine Hydrochloride ; Benzamycin Gel Benztropine Bepanthen Nasal Oint Berapamilo Betagan Levobunolol ; Betaloc Metoprolol, Tolrol ; Betaloc Metoprolol, Tprol ; Betamethasone Dipropionate Cr. Betapace Sotalol ; Betapace Sotalol ; Betaseron Cannot Ship due to refrigeration ; Betaxolol Susp. Bethanechol Bethanechol Betimol Opth. Soln. Betoptic Betaxolol ; Betoptic Betaxolol ; Betoptic-S Betoptic-S Bextra Valdecoxib ; Bextra Valdecoxib ; Biaxin Clarithromycin ; Biaxin Clarithromycin ; Bicillin LA Inj. Blephamide Opthalmic Oint. Botox Brevoxyl Cr. Bricanyl Turbohaler Bronkaid Bumex Buprenex Burinex Bumetanide ; Burinex Bumetanide ; Buspar Buspirone ; Buspar Buspirone ; Butalbital APAP Caffeine - CPO Cafergot Supp. Calan SR See Verapamil SR ; Calcijex Calcitonin Nasal Spray Caltrate Camptosar Cantharone Plus Capex Shampoo Fluocinolone Acetonide ; 1% 600 MG 1 60 7.5 ML 120 ML $75.51 $21.00 $270.91 $74.27 $44.76 .2 MG 12 $40.70 1 MG 5 MG 100 $34.84 $103.65 $127.30 $85.01 .5 MG 200 DS $27.66 0.25% 50 MG 25 MG 0.25% .5% MG 20 MG 250 MG 500 MG 5 ML 100 X 2 3.5 GM $24.07 $37.42 $168.98 $189.10 $367.81 $101.01 $24.09 .5% 50 MG 100 MG 0.05% 80 MG 160 MG 10 ML 100 50 GM 100 15 X 3 100 $29.50 $78.11 $52.04 $40.19 $37.58 $56.92 $40.06 $78.26 $84.67 $28.20 $24.41 $35.82 1 MG 20 MG 100 23.3 GM 100 $44.68 $23.11 $33.40 $12.86. Figure 7. Mortality curve from post hoc subgroup analysis of patients with severe heart failure in the Metoprolol Controlled Release Extended Release CR XL ; Randomized Intervention Trial in Congestive Heart Failure MERIT-HF ; . Adapted with permission from Goldstein et al.40 and vioxx. You could be at increased risk for seizure, psychosis, or a fatal drug interaction.

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Quantified by reversed phase chromatography of aliquots withdrawn from electrolyzed 179 mg L 1 clofibric acid solutions of pH 3.0 and pH 12.0 at 100 mA cm 2 and at 35 C using Pt and BDD. Clofibric acid solutions under the conditions referred were electrolyzed by AO with Pt and BDD to obtain the ion exclusion chromatograms reflecting the carboxylic acids accumulated. Due to the formation of 2 hydroxyisobutyric acid, a particular carboxylic acid not deeply studied by other authors, during the degradation of the pharmaceutical, an electrolysis of this acid with BDD was carried out at pH 3.0, at 100 mA cm 2 and at 35 C clarify its oxidation pathway and trazodone.

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Zestoretic [lisinopril HCTZ] 287. Zestril [lisinopril] 288. Ziac [bisoprolol HCTZ] 289. Zocor [simvastatin] 290. Zoloft [sertraline]. In Phillips v. Cricket Lighters, 576 Pa. 644, 841 A.2d 1000 2003 ; , on remand to Phillips v. Cricket Lighters, 852 A.2d 365 Pa. Super. Jun 10, 2004 ; , appeal granted by Phillips v. Cricket Lighters, A.2d -, 2004 WL 2386829 Pa. Oct 26, 2004 ; , the Pennsylvania Supreme Court affirmed the Superior Court s order reinstating the plaintiff s design defect claim sounding in negligence and at the same time reversed the Superior Court s reinstatement of the strict liability design defect claim, finding the product at issue to be safe for its intended users.1 In Phillips, a minor-child apparently started a fire with a Cricket cigarette lighter that was not equipped with child resistant features, and this fire resulted in the death of his mother and siblings. The guardian of the minor-child and the Administratrix of the estate of the minor-child s deceased siblings filed a lawsuit against the manufacturer and distributors of the lighter, asserting various claims including design defect claims under both negligence and strict liability theories. The Supreme Court in Phillips held that the strict liability claim was properly dismissed on summary judgment because the lighter was safe for its intended users. However, the Court held that the Superior Court erred in granting summary judgment as to the negligent design claim simply because the strict liability claim had been dismissed. The Phillips Court ruled that a finding of no defect does not perforce require dismissal of the negligence claim, without first analyzing the elements of negligence. The Court reasoned that the focus under a strict liability theory is the product itself, whereas for a negligence cause of action the inquiry is concerned with the reasonableness of a defendant s conduct: Were we to dispose of a negligence claim merely by an examination of the product, without inquiring into the reasonableness of the manufacturer s conduct in creating and distributing such a product, we would be divorcing our analysis from the elements of the tort. Thus, as the elements of the causes of action are quite distinct, it would be illogical for us to dispose of [plaintiff s] negligence claim based solely on our disposition of her strict liability claim. Instead, we must examine the law of negligence and determine whether the trial court erroneousl y det ermi ned t hat [plaintiff s] negligence claim failed as a matter of law. Phillips, 841 A.2d at 1008. After weighing the necessary factors tending to establish the elements of the plaintiff s negligence claim, the Court concluded that a jury question existed as to whether the manufacturers were negligent in designing a butane lighter that lacked a child safety device. On these grounds, the Court affirmed the Superior Court s reinstatement of the negligence claim. Justice Saylor wrote a separate, concurring opinion, which was joined by Justices Castille and Eakin, in which he joined the majority disposition of the strict liability and negligence claims under present law. Id. at 1012. The thrust of Justice Saylor s concurrence was devoted to an analysis of alternatives and readily accessible, corrective measures to Pennsylvania s strict products liability jurisprudence, which under its present state divorces negligence concepts from consideration in a strict liability action. Id. Justice Saylor opined that the Restatement Third ; of Torts, which utilizes the negligence concept of risk-utility balancing in design defect litigation, illuminates the most viable route to providing essential clarification and remediation to Pennsylvania law in this area. Id. at 1019. Justice Newman wrote separately and concurred with the majority s ruling that concepts of negligence have no place in a strict products liability case and that the strict liability claim must fail because the lighter was safe for its intended users. Id. at 1023. However, Justice Newman dissented from the majority that the plaintiff s negligence causes of action be allowed to remain, opining that under the law of negligence a defendant cannot be liable in damages for placing into the.
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Norepinephrine Is a Potent Inducer of ET-1 Gene Expression in Cardiac Myocytes--To determine whether stimulation of both - and -adrenergic receptors by NE would induce the expression of the ET-1 gene in cardiac myocytes, primary cardiac myocytes from neonatal rats were stimulated with saline or 10 6 for 24 h. Then, we examined the expression of the ET-1 gene by Northern blot using a cDNA probe for the preproET-1 mRNA. We performed these experiments using three independent preparations of cardiac myocytes. As shown in Fig. 1, stimulation with NE markedly increased the expression of the ET-1 gene in cardiac myocytes lane 2 ; compared with the saline-stimulated state lane 1 ; . To determine whether the NE-stimulated increase in the ET-1 gene expression is mediated through an - or -adrenergic receptor, cardiac myocytes were stimulated with NE in the presence of an -adrenergic receptor antagonist, prazosin 10 6 M ; , -adrenergic receptor antagonist, metoprolol 10 6 M ; , for 24 h. Administration of prozosin in addition to NE only slightly reduced ET-1 gene expression lane 3 ; . In contrast, administration of metoprolol in addition to NE severely attenuated the expression lane 4 ; . NE, prazosin, or metoprolol did not alter the expression of the ubiquitously and constitutively expressed GAPDH gene. We confirmed that in our preparation, more than 90% of the NEstimulated cells were positive for staining with HHF35, which recognizes the -actin of cardiac muscle cells but not that of fibroblasts. These data indicate that NE, an important neurohormonal factor activated in congestive heart failure, is a potent inducer of ET-1 gene expression in cardiac myocytes and that NE-responsive ET-1 expression is mediated predominantly through a -adrenergic receptor-dependent pathway. NE-responsive ET-1 Transcription Is Mediated Predominantly through a -Adrenergic Receptor-dependent Pathway--To determine if transcriptional activation could account. 52. Sacks FM, Pfeffer MA, Moye LA, Rouleau JL, Rutherford JD, Cole TG, et al. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. N Engl J Med. 1996; 335: 1001-1009. The Long-Term Intervention with Pravastatin in Ischaemic Disease LIPID ; Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med. 1998; 339: 1349-1357. Aronow WS. Rationale for lipid-lowering in older patients with or without CAD. Geriatrics. 2001; 56 9 ; : 22-30. 55. McKenney JM. New guidelines for managing hypercholesterolemia. J Pharm Assoc. 2001; 41: 596-607. Executive summary of the Third Report of the National Cholesterol Education Program NCEP ; Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults Adult Treatment Panel III ; . JAMA. 2001; 285: 2486-2497. Frick MH, Elo O, Haapa K, Heinonen OP, Heinsalmi P, Helo P, et al. Helsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease. N Engl J Med. 1987; 317: 1237-1245. Rubins HB, Robins SJ, Collins D, Fye CL, Anderson JW, Elam MB, et al. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. N Engl J Med. 1999; 341: 410-418. ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial ALLHAT ; . JAMA. 2002; 288: 2981-2997. Konzem SL, deVore VS, Bauer DW. Controlling hypertension in patients with diabetes. Fam Phys. 2002; 66: 1209-1214. Gottlieb SS, McCarter RJ. Comparative effects of three beta blockers atenolol, metoprolol and propanolol ; on survival after acute myocardial infarction. J Cardiol. 2001; 87: 823-826. UK Prospective Diabetes Study UKPDS ; Study Group. Efficacy of atenolol and captopril in reducing risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 39. BMJ. 1998; 317: 713-720. Pitt B. The anti-ischemic potential of angiotensin-converting enzyme inhibition: insights from the Heart Outcomes Prevention Evaluation trial. Clin Cardiol. 2000; 23 suppl IV ; : IV9-IV14. 64. Niskanen L, Hedner T, Hansson L, Lanke J, Niklason A, for the CAPPP Study Group. Reduced cardiovascular morbidity and mortality in hypertensive diabetic patients on first-line therapy with an ACE inhibitor compared with a diuretic beta-blocker-based treatment regimen. A subanalysis of the Captopril Prevention Project. Diabetes Care. 2001; 24: 2091-2096. Kaplan NM. Angiotensin II receptor antagonists in the treatment of hypertension. Fam Phys. 1999; 60: 1185-1190. Brenner BM, Cooper ME, de Zeeuw D, Keane WF, Mitche WE, Parving HH, et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med. 2001; 345: 861-869. Lewis EJ, Hunsicker LG, Clarke WR, Berl T, Pohl MA, Lewis JB, et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med. 2001; 345: 851-860. Hansson L, Hedner T, Lund-Johansen P, Kjeldsen SE, Lindholm LH, Syvertsen JO, et al. Randomised trial of effects of calcium antagonists compared with diuretics and beta-blockers on cardiovascular morbidity and mortality in hypertension: the Nordic Diltiazem NORDIL ; study. Lancet. 2000; 356: 359-365. Pahor M, Psaty BM, Alderman MH, Applegate WB, Williamson JD, Cavazzini C, et al. Health outcomes associated with calcium antagonists compared with other first-line antihypertensive therapies: a meta-analysis of randomised controlled trials. Lancet. 2000; 356; 1949-54. Hansson L, Zanchetti A, Carruthers SG, Dahlf B, Elmfeldt D, Julius S, et al. Effects of intensive blood-presssure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment HOT ; randomised trial. Lancet. 1998; 351: 1755-1762. Tuomilehto J, Rastenyte D, Birkenhger WH, Thijs L, Antikainen R, Bulpitt CJ, et al. Effects of calcium-channel blockade in older patients with diabetes and systolic hypertension. N Engl J Med. 1999; 340: 677-684. Wang JG, Staessen JA, Gong L, Liu L, for the Systolic Hypertension in China Syst-China ; Collaborative Group. Chinese trial on isolated systolic hypertension in the elderly. Arch Intern Med. 2000; 160: 211-220. Antithrombotic Trialists' Collaboration. 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