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Nature Lond. ; . 307: 273. 6. Chung, I.Y., J.G. Norris, and E.T. Benveniste. 1991. Differential TNF-c~ expressionby astrocytes from experimental allergic encephalomyelitis-susceptibleand -resistant rat strains Exl~ Med. 173: 801. 7. Frohman, E.M., T.C. Frohman, M.L. Dustin, B. Vayuvegula, B. Choi, A. Gupta, S. van den Noort, and S. Guputa. 1989. The induction of intercellular adhesion molecule 1 ICAM-1 ; expression on human fetal astrocytes by interferon-gamma, tumor necrosis factor-alpha, lymphotoxin, and interleukin-l: relevanceto intracerebralantigen presentation.J. Neuroimmunol. 23: 117. 8. Janeczko, K. 1991. The proliferative response of S-100 protein positive glial ceils to injury in the neonatal rat brain. Brain Res. 564: 86. 9. Petito, C.K., S. Morgello, J.C. Felix, and M.L. Lesser. 1990. The two patterns of reactive astrocytosis in postischemic rat brain, f Cerett Blood Flow Meta~t 10: 850. 10. Koga, S., S. Ogawa, K. Kuwabara, J. Brett J., L, A. Leavy, J. Ryan, Y. Koga, J. Plocinski, W. Benjamin, D.K. Burns, et al. 1992. Synthesis and release of interleukin 1 by reoxygenated human mononuclear phagocytes. J. Clin. Invest. 90: 1007. 11. Colletti, L., D.G. Remick, G. Burtch, S.L. Kunkel, R.M. Strieter, and D. Campbell, Jr. 1990. Role of tumor necrosis factor-c~in the pathophysiologic alterations after hepatic ischemia reperfusion injury in the rat. f Clin. Invest. 85: 1936. 12. Youker, K., C.W. Smith, D.C. Anderson, D. Miller, L.H. Michael, R.D. Rossen, and M.L. Entman. 1992. Neutrophil adherence to isolated adult cardiac monocytes. Induction by cardiac lymph collectedduring ischemia and ~erfusion.J. Clin. Invest. 89: 602. 13. Benveniste, E.T. 1992. Inflammatory cytokines within the central nervous system: sources, function, and mechanism of action. Am. J. Physiol. 263: C1. 14. McCarthy, K.D., and J. Vellis. 1980. Preparation of separate and astroglial and oligodendrogial cell cultures from rat cerebral tissue. J. Cell Biol. 85: 890. 15. Frei, K., C. Siepl, P. Groscurth, S. Bodmer, C. Schwerdel, and A. Fontana. 1987. Antigen presentation and tumor cytotoxicity by interferon-gamma-treated microglial cells. Eur. J. Immunol. 17: 1271. 16. Ogawa, S., G. Herwig, C. Esposito, A.P. Macaulay, J. Brett, and D. Stern. 1990. Hypoxia modulates the barrier and coagulant function of cultured bovine endothelium.J. Clin. Invest. 85: 1090. 17. Madri, J.A., B.M. Pratt, and A.M. Tucker. 1988. Phenotypic modulation of endothelialcellsby transforming growth factor-~ depends upon the composition and organization of the extracellular matrix, f Cell Biol. 106: 1375. 18. Ueda, H., T. Hashimoto, E. Furuya, K. Tagawa, K. Kitagawa, M. Matsumoto, S. Yoneda, K. Kimura, and T. Kamda. 1988. Changes in aerobic and anaerobic ATP-synthesizing activities in hypoxic mouse brain. J. Biochem. Tokyo ; . 104: 81. 19. Lowry, O.H., N.J. Rosenbrough, L.A. Farr, and R.J. Randull. 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193: 265. 20. Nakai, S., K. Mizuno, M. Kenta, and Y. Hirai. 1988. A simple, sensitivebioassayfor the detection ofinterleukin-1 using human melanoma A375 cell line. Biochem. Biophys. Res. Commun. 154: 1189. 21. Kull, F.C., Jr., and J.M. Besterman. 1990. Drug-induced al2307 Maedaet al, because exelon employees.
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